Synthesis, Characterization and Biological Studies of Porphyrinyloxovanadium(IV)benzimidazole Complexes
نویسنده
چکیده
The six-coordinate oxovanadium(IV) complexes [VO(RTPP)(L)] (where R=H, methyl, methoxy and chloro groups and L= methyl and ethyl substituted benzimidazoles) were prepared by reacting the ligands; 2-methylbenzimidazole and 2-ethylbenzimidazole with various VO(RTPP). The complexes were characterized by elemental analysis, IR, UV–Vis and H & C NMR. All complexes show V=O stretching vibrations between 932 and 1050 cm. The presence of three d–d transitions occurring between 400 and 625 nm confirm the d electronic configuration of the complexes. Based on spectral and magnetic studies, an octahedral geometry is assigned for all the complexes. The electrochemical behavior of some complexes was also investigated using cyclic voltammetry. The complexes exhibit positive antibacterial activities but showed negative antifungal activity. The free-radical-scavenging ability of the metal complexes was also determined by their interaction with the stable free radical 2,2-diphenyl-1-picrylhydrazyl, which showed encouraging antioxidant activities.
منابع مشابه
Synthesis and Spectroscopic Characterization of Some New Coordination Compounds of Organotin (IV) with Carbohydrazones
Some new coordination compounds of tin(IV) having general formula [SnBu2 (L)2 ] (where L = carbohydrazone ligand) have been synthesized by the reaction of dibutyltin oxide with carbohydrazone ligands with the ratio of 1:2 (metal- ligand) using dry benzene as a reaction medium. The newly synthesized complexes were characterized by elemental analysis, molecular weight determinations, conductivity...
متن کاملSynthesis, Characterization and Biological Studies of 2-(4-Nitrophenylaminocarbonyl)Benzoic Acid and Its Complexes with Cr(III), Co(II), Ni(II), Cu(II) and Zn(II)
Cr(III), Co(II), Ni(II), Cu(II) and Zn(II) salts of 2-(4-nitrophenylaminocarbonyl)benzoic acid were characterized by physical, analytical and spectroscopic studies and checked for their in-vitro antimicrobial activity against three bacterial strains, Mycobacterium smegmatis (Gram +ve), Escherichia coli (Gram -ve), Pseudomonas aeuroginosa (Gram -ve) and three fung...
متن کاملSynthesis, Spectral Characterization and DFT Calculations of New Co(II) Complexes Derived from Benzimidazoles
The synthesis, characterization and quantum-chemical investigations of two new Co(II) complexesderived from fluorescent benzimidazoles have been reported. Two new fluorescentheterocyclic ligands were synthesized from the reduction of imidazo[4',5':3,4]benzo[1,2-c]isoxazole derivatives, and characterized by elemental analyses, IR, mass, and NMR spectra. Coordination of the bidentate ligands ...
متن کاملNovel Pt(II) Complex and Its Pd(II) Aanalogue. Synthesis, Characterization, Cytotoxicity and DNA-interaction
The ability of small molecules to perturb the natural structure and dynamics of nucleic acids is intriguing and has potential applications in cancer therapeutics. This work reports the synthesis, characterization, cytotoxicity and DNA-binding studies of two cytotoxic and intercalative [M(bpy)(pyrr-dtc)]NO3 complexes (where M = Pt(II) and Pd(II), bpy = 2,2´-bipyridine and pyrr-dtc = p...
متن کاملSynthesis, Spectral, Biological and Theoretical Investigation of Some New Sn (IV) Complexes with Schiff Base Ligands Containing NNOS Coordination Sphere
New tin (IV) complexes of empirical formula, [Cl2 Me2 Sn(H2 L)1-3], where ((H2 L)1-3: Methyl-2- {[1-methyl-2-(2-hydroxy-3-methoxyphenyl)methylidynenitrilo]ethyl}amino-1-cyclopentenedithiocarboxylate [H2cd3OMesalMeen], Methyl-2-{[1-methyl-2-(2-hydroxy-4-methoxyphenyl)methylidynenitrilo]ethyl}amino-1-cyclopentenedithiocar-boxylate, [H2 cd4OMesalMeen], Methyl-2-{[1-methyl-2-(2-hydroxy-5-methoxyphe...
متن کامل